Figure 3
From: Leiomyosarcoma of the inferior vena cava: Clinical experience with four cases

Photomicrograph of the edge of the tumour (× 40). (A). The tumour is composed of spindle cells which show nuclear pleomorphism with occasional giant nuclei (Hematoxylin and eosin × 200), (B). Immunohistochemistry for epithelial marker AE1/AE3 (C), and for S100 (D) is negative, but tumor is strongly positive for smooth muscle marker smooth muscle actin(E).