Table 1 Characteristics of the 575 patients with PDAC
Characteristics | FPR High (N = 335) | FPR Low (N = 228) | P value |
|---|---|---|---|
Age | 0.240 | ||
< 65 | 214 (63.9%) | 157 (68.9%) | |
≥ 65 | 121 (36.1%) | 71 (31.1%) | |
Gender | 0.863 | ||
Female | 145 (43.3%) | 101 (44.3%) | |
Male | 190 (56.7%) | 127 (55.7%) | |
CA199 | 0.161 | ||
< 100 (U/ml) | 125 (37.3%) | 99 (43.4%) | |
≥ 100 (U/ml) | 210 (62.7%) | 129 (56.6%) | |
CEA | 0.706 | ||
< 5 (U/ml) | 236 (70.4%) | 164 (71.9%) | |
≥ 5 (U/ml) | 99 (29.6%) | 64 (28.1%) | |
pT stage | 0.660 | ||
T1 | 38 (11.3%) | 30 (13.2%) | |
T2 | 212 (63.3%) | 136 (59.6%) | |
T3 | 85 (25.4%) | 62 (27.2%) | |
pN stage | 0.035 | ||
N0 | 217 (64.8%) | 171 (75.0%) | |
N1-N2 | 118 (35.2%) | 48 (25.0%) | |
Location | < 0.001 | ||
Body/Tail | 74 (22.1%) | 104 (45.6%) | |
Head | 261 (77.9%) | 124 (54.4%) | |
Differentiation | 0.033 | ||
Moderate | 123 (36.7%) | 101 (44.3%) | |
Poor | 162 (46.6%) | 105 (46.1%) | |
Well | 57 (16.7%) | 22 (9.6%) | |
Extrapancreatic invasion | 0.387 | ||
No | 140 (41.8%) | 104 (45.6%) | |
Yes | 195 (58.2%) | 124 (54.4%) | |
Lymphovascular invasion | 0.592 | ||
No | 271 (80.9%) | 180 (78.9%) | |
Yes | 64 (19.1%) | 48 (21.1%) | |
Neural invasion | 0.117 | ||
No | 130 (38.8%) | 104 (45.6%) | |
Yes | 205 (61.2%) | 124 (54.4%) | |
Adjuvant chemotherapy | 0.262 | ||
No | 126 (37.6%) | 77 (33.8%) | |
Gemcitabine-based | 175 (52.2%) | 118 (51.8) | |
(m)-FOLFIRINOX | 34 (10.1%) | 33 (14.5%) | |
Resectability status | 0.581 | ||
Resectable | 297 (88.7%) | 206 (90.4%) | |
Borderline resectable | 38 (11.3%) | 22 (9.6%) | |
Preoperative NLR | < 0.001 | ||
< 1.80 | 88 (26.3%) | 98 (43.0%) | |
≥ 1.80 | 247 (73.7%) | 130 (57.0%) | |
Preoperative PLR | < 0.001 | ||
< 170.8 | 184 (54.9%) | 180 (78.9%) | |
≥ 170.8 | 151 (45.1%) | 48 (21.1%) |