Table 2 Surgical, radiological, and pathological outcomes of patients who received neoadjuvant immunochemotherapy followed by surgery. Radiological outcomes: ORR = Overall Response Rate, CR = Complete Response, PR = Partial Response, SD = Stable Disease, PD = Progressive Disease. Pathological outcomes: MPR = Major Pathological Response, PCR = Pathological Complete Response
Covariate | n = 31 |
|---|---|
Post stage, n (%) | |
TxN0M0 | 2 (6.4%) |
Ib | 1 (3.2%) |
IIa | 1 (3.2%) |
IIb | 7 (22.5%) |
IIIa | 19 (61.2%) |
IIIb | 1 (3.2%) |
Downstage, n (%) | |
No | 13 (42.0%) |
Yes | 18 (58.0%) |
ORR, n (%) | |
No | 10 (27.6%) |
Yes | 21 (72.4%) |
Radiological response, n (%) | |
Unknown | 1 (3.2%) |
CR | 2 (6.4%) |
PD | 2 (6.4%) |
PR | 19 (61.5%) |
SD | 7 (22.5%) |
Type of Surgery, n (%) | |
Lobectomy | 26 (83.8%) |
Sleeve lobectomy | 4 (12.9%) |
Lung autotransplantation | 1 (3.2%) |
Days (d) | |
Mean (min, max) | 5.5 (2,10) |
Surgery time (min) | |
Mean (min, max) | 199.7 (105,595) |
Blood loss (ml) | |
Mean ((min, max) | 44.8 (10,200) |
Volume of drainage (ml) | |
Mean (min, max) | 646.1 (220,1200) |
DFS (months) | |
Mean (min, max) | 17.4 (5,40) |
Pathological response, n (%) | |
MPR | 8 (25.8%) |
PCR | 2 (6.4%) |