Table 4 Univariate and multivariate Cox regression analyses of risk factors in breast cancer patients undergoing chemotherapy

Menopausal status at diagnosis (Premenopausal vs. Postmenopausal)

1.328 (0.836–2.109)

0.229

Age (< 50 years vs. ≥ 50 years)

1.051 (0.107–2.335)

0.159

Hepatitis Infection (yes vs. no)

1.366 (0.921–1.810)

0.135

Grade of histology (III vs. I-II)

1.344 (1.017–1.603)

0.018

Lymphovascular invasion (yes vs. no)

3.474 (1.869–6.458)

 < 0.001

2.484 (1.472–3.570)

0.023

Radiotherapy (yes vs. no)

2.136 (0.253–4.042)

0.405

Ki67 (≥ 30% vs. < 30%)

2.578 (1.496–3.441)

 < 0.001

1.485 (1.234–1.749)

 < 0.001

Triple negative

3.065 (1.748–4.374)

 < 0.001

2.542 (1.586–4.107)

 < 0.001

TNM stage (3 vs. 1–2)

3.137 (1.965–5.008)

 < 0.001

Treatment after recurrence and metastasis (surgery vs. no surgery)

2.110 (0.112–4.307)

0.072

High GSH intake

3.487 (1.176–5.790)

 < 0.001

2.927 (1.344–4.589)

 < 0.001