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Table 1 Pretreatment features of cases in the EP300-mutated poor response, EP300 wild-type poor response, and EP300 wild-type well response groups

From: Esophageal squamous cell carcinoma with EP300 mutations displays distinct genetic characteristics relevant to neoadjuvant chemoradiotherapy

Features

N

EP300 mutated

poor response (N, %)

 

EP300 wild-type

poor response (N, %)

 

EP300 wild-type

well response (N, %)

P

Age (years)

      

0.179

≤ 60

10 (38.5)

1 (25.0)

 

1 (14.3)

 

8 (53.3)

 

>60

16 (61.5)

3 (75.0)

 

6 (85.7)

 

7 (46.7)

 

Gender

      

0.223

Male

20 (76.9)

3 (75.0)

 

7 (100)

 

10 (66.7)

 

Female

6 (23.1)

1 (25.0)

 

0 (0)

 

5 (33.3)

 

Smoking history

      

0.791

Yes

17 (65.4)

3 (75.0)

 

5 (71.4)

 

9 (60.0)

 

No

9 (34.6)

1 (25.0)

 

2 (28.6)

 

6 (40.0)

 

Alcohol consumption

      

0.600

Yes

16 (61.5)

3 (75.0)

 

5 (71.4)

 

8 (53.3)

 

No

10 (38.5)

1 (25.0)

 

2 (28.6)

 

7 (46.7)

 

Site of ESCC

      

0.228

up

3 (11.5)

0 (0)

 

2 (28.6)

 

1 (6.7)

 

middle

16 (61.5)

2 (50.0)

 

5 (71.4)

 

9 (60.0)

 

lower

7 (26.9)

2 (50.0)

 

0 (0)

 

5 (33.3)

 

cT Stage

      

0.239

2–3

23 (88.5)

4 (100)

 

5 (71.4)

 

14 (93.3)

 

4

3 (11.5)

0 (0)

 

2 (28.6)

 

1 (6.7)

 

cN Stage

      

0.105

0–1

17 (65.4)

3 (75.0)

 

2 (28.6)

 

12 (80.0)

 

2

9 (34.6)

1 (25.0)

 

5 (71.4)

 

3 (20.0)