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Fig. 2 | World Journal of Surgical Oncology

Fig. 2

From: Single-cell transcriptomics unveils multifaceted immune heterogeneity in early-onset versus late-onset cervical cancer

Fig. 2

Characteristics of epithelial cells in EOCC and LOCC. (A-B) t-SNE plots of all epithelial cells, color-coded by cluster (A) and by group (B). (C) Bar plot illustrating the proportions of the nine epithelial clusters within each group. (D) Bubble plot showing significantly enriched KEGG pathways of DEGs in epithelial cells between EOCC and LOCC. (E) Violin plots depicting differentially expressed chemokines between EOCC and LOCC. (F) Kaplan-Meier curves illustrating the association between chemokine expression and cancer-specific survival (CSS). (G) Violin plots displaying differentially expressed HLA molecules between EOCC and LOCC. (H) Kaplan-Meier curves demonstrating the association between HLA expression and CSS. (I) Violin plots showing differentially expressed immune checkpoints between EOCC and LOCC. (J) Heatmap comparing the activity of immune-related TF regulons between EOCC and LOCC. (K) Heatmap visualizing CNVs across 22 chromosomes in the eight analyzed samples

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World Journal of Surgical Oncology

ISSN: 1477-7819

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