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Fig. 5 | World Journal of Surgical Oncology

Fig. 5

From: Single-cell transcriptomics unveils multifaceted immune heterogeneity in early-onset versus late-onset cervical cancer

Fig. 5

Characteristics of fibroblasts in EOCC and LOCC. (A-C) t-SNE plots of fibroblasts, distinguished by cluster (A), cell type (B), and group (C). (D) t-SNE plots illustrating the expression of canonical markers across fibroblast subtypes. (E) Bubble plots depicting marker gene expression across fibroblast subtypes. (F) Pie charts displaying the distribution of fibroblast subtypes within EOCC and LOCC. (G) Bubble plots representing significantly enriched KEGG pathways of DEGs in fibroblasts between EOCC and LOCC. (H-I) Violin plots showing differentially expressed chemokines and HLA molecules in fibroblasts between EOCC and LOCC. (J-L) Pseudotime trajectory and cytoTRACE analysis of fibroblasts from EOCC and LOCC. (M) Box plot comparing cytoTRACE scores between EOCC and LOCC derived fibroblasts. (N) Dynamic expression changes in chemokines along the pseudotime axis

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World Journal of Surgical Oncology

ISSN: 1477-7819

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