Table 1 Characteristics of patients who achieve TO versus non-TO

PATIENTS CHARACTERISTICS

Age*

64 (56.8–67.1)

58.1 (55.1–68.0)

< 0.0001

BMI median (IQR)

25.9 (22.6–29)

25.9 (22.8–29.6)

0.45

ASA

0.12

1

2

3

4

8 (5.0)

63 (39.1)

85 (52.8)

5 (3.1)

7 (3.4)

105 (51.5)

88 (43.1)

4 (2.0)

Charlson age score*

2(2–3)

2(1–3)

< 0.001

Histology

0.23

• Low grade

• High grade

• Endometroid

• Others

1 (0.3)

147 (40.3)

3 (0.8)

2 (0.5)

0 (0.0)

188 (51.5)

7 (1.9)

8 (2.2)

Preoperative DATA

Hb * g/dL

12 (1.8–12)

12 (11–12)

0.68

Neutrophils*) l/mm³

5305 (3810–7230)

5390 (3990–6810)

0.96

Lymphocytes * l/mm³

1410 (1220–1890)

1410 (1190–1480)

0.46

Platelets *x10³/µL

232.000 (194.000–29.000)

22.000 (165.000-287.000)

0.34

CEA * ng/mL

1.93 (1.40–2.40)

2 (1.3–2.6)

0.88

CA 125 * ng/mL

53 (23–236)

31 (16–163)

0.04

CA19.9 *ng/mL

22.65 (13.6-48.45)

11 (7–35)

0.06

HE4 *U/mL

136 (94–193)

71 (63–100)

0.02

INTRAOPERATIVE DATA

Surgical time (min)

350 (300–450)

300 (250–375)

< 0.0001

Total PCI

< 0.0001

< 10

11–20

> 20

51 (14)

59 (16.2)

50 (13.7)

143 (39.3)

51 (14.0)

10 (2.7)

PCI median (IQR)

15 (8–22)

6 (3–12)

< 0.0001

Intestinal resection

< 0.0001

No

Yes

79 (21.6)

82 (22.5)

153 (41.9)

51 (14)

Anastomosis number

< 0.0001

1

2

3

4

80 (21.9)

60 (16.4)

19 (5.2)

2 (0.5)

155 (42.5)

43 (11.8)

6 (1.6)

0 (0)

HIPEC

0.04

No

Yes

35 (9.6)

126 (34.5)

28 (7.7)

176 (48.4)

HIPEC

0.14

Cisplatin

Paclitaxel

42 (11.5)

84 (23)

73 (20)

102 (27.9)

Time to return chemotherapy*

6 (5–8)

4 (4–6)

< 0.0001

POSTOPERATIVE RESULTS

Clavien Dindo Complications **

< 0.0001

0

I

II

IIIa

IIIb

Iva

IVb

V

30 (8.2)

2 (0.5)

58 (15.9)

37 (1.1)

15 (4.1)

4 (1.1)

8 (2.2)

7 (1.9)

122 (33.4)

10 (2.7)

72 (19.7)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

C reactive protein (CRP) 3º day*

124 (101.3-116.9)

63.5 (31.9–86.5)

0.003

C reactive protein (CRP) 5º day*

117.1 (84.1-196.2)

36.4 (10–45)

0.001

Medical complication

< 0.001

No

yes

104 (28.5)

57 (15.6)

187 (51.2)

17 (4.7)

Surgical complication

< 0.001

No

Yes

95 (26)

66 (18.1)

189 (51.8)

15 (4.1)

Fistula or dehiscence

0.01

No

Yes

156 (42.7)

5 (1.4)

204 (56.4)

0 (0.0)

SSI superficial

0.14

No

YES

156 (42.7)

5 (1.4)

202 (55.3)

2 (0.5)

Ileus

0.14

No

Yes

145 (39.7)

16 (4.4)

197 (54)

7 (1.9)

Catheter infection

0.05

No

Yes

158 (43.6)

3 (0.8)

204 (55.9)

0 (0.0)

Relapse

0.32

No

Yes

52 (14.2)

109 (29.9)

76 (2.8)

128 (35.1)

Length of stay (days) **

11 (7–14)

7 (5–8)

< 0.001

Survival in months after surgery median (IQR)

27 (14-48.2)

41 (24.5–67)

< 0.0001