Table 7 Comparison of common AEs in two groups (n, %)
Chemotherapy Group (n = 30) | Immunotherapy Combined Chemotherapy Group (n = 30) | P (Grade 1 ∼ 4) | P (Grade 3 ∼ 4) | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
Type of AEs | Grade 1 ∼ 4 (n) | Grade 1 ∼ 4 Incidence (%) | Grade 3 ∼ 4 (n) | Grade 3 ∼ 4 Incidence (%) | Grade 1 ∼ 4 (n) | Grade 1 ∼ 4 Incidence (%) | Grade 3 ∼ 4 (n) | Grade 3 ∼ 4 Incidence (%) | ||
Overall Incidence | 30 | 100 | 14 | 47 | 30 | 100 | 18 | 60 | 1.000 | 0.301 |
RCCEP | 0 | 0 | 0 | 0 | 24 | 80 | 0 | 0 | <0.001 | 1.000 |
Anemia | 19 | 63 | 3 | 10 | 23 | 77 | 4 | 13 | 0.260 | 1.000 |
Decreased White Blood Cell Count | 17 | 57 | 3 | 10 | 22 | 73 | 6 | 20 | 0.176 | 0.472 |
Decreased Neutrophil Count | 18 | 60 | 6 | 20 | 21 | 70 | 6 | 20 | 0.417 | 1.000 |
Decreased Lymphocyte Count | 13 | 43 | 5 | 17 | 17 | 57 | 6 | 20 | 0.302 | 0.739 |
Hypoalbuminemia | 16 | 53 | 0 | 0 | 15 | 50 | 1 | 3 | 0.796 | 1.000 |
Decreased Platelet Count | 14 | 47 | 2 | 7 | 12 | 40 | 2 | 7 | 0.602 | 1.000 |
Hyponatremia | 14 | 47 | 0 | 0 | 11 | 37 | 0 | 0 | 0.432 | 1.000 |
Hypothyroidism | 1 | 3 | 0 | 0 | 10 | 33 | 0 | 0 | 0.003 | 1.000 |
Pneumonia | 10 | 33 | 4 | 13 | 10 | 33 | 7 | 23 | 1.000 | 0.317 |
Hyperuricemia | 6 | 20 | 0 | 0 | 8 | 27 | 0 | 0 | 0.542 | 1.000 |
Vomiting | 6 | 20 | 0 | 0 | 8 | 27 | 1 | 3 | 0.542 | 1.000 |
Diarrhea | 2 | 7 | 0 | 0 | 6 | 20 | 1 | 3 | 0.254 | 1.000 |
Hyperlipidemia | 2 | 7 | 0 | 0 | 5 | 17 | 0 | 0 | 0.424 | 1.000 |
Rash | 0 | 0 | 0 | 0 | 5 | 17 | 0 | 0 | 0.052 | 1.000 |
Constipation | 0 | 0 | 0 | 0 | 5 | 17 | 0 | 0 | 0.052 | 1.000 |
Elevated Blood Urea | 4 | 13 | 0 | 0 | 4 | 13 | 0 | 0 | 1.000 | 1.000 |
Elevated Creatinine | 1 | 3 | 0 | 0 | 4 | 13 | 0 | 0 | 0.353 | 1.000 |
Dizziness | 1 | 3 | 0 | 0 | 4 | 13 | 0 | 0 | 0.353 | 1.000 |
Insomnia | 0 | 0 | 0 | 0 | 4 | 13 | 0 | 0 | 0.112 | 1.000 |
Hypokalemia | 4 | 13 | 0 | 0 | 3 | 10 | 0 | 0 | 1.000 | 1.000 |
Abdominal Pain | 3 | 10 | 0 | 0 | 3 | 10 | 0 | 0 | 1.000 | 1.000 |
Fatigue | 1 | 3 | 0 | 0 | 3 | 10 | 0 | 0 | 0.612 | 1.000 |
Esophageal Fistula | 3 | 10 | 3 | 10 | 2 | 7 | 2 | 7 | 1.000 | 1.000 |
Elevated ALT | 4 | 13 | 0 | 0 | 2 | 7 | 0 | 0 | 0.671 | 1.000 |
Elevated AST | 4 | 13 | 0 | 0 | 1 | 3 | 0 | 0 | 0.353 | 1.000 |