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Table 1 Patient characteristics

From: Evaluation of the details and importance of lymphatic, microvascular, and perineural invasion in patients with non-functioning pancreatic neuroendocrine neoplasms based on tumor size and the 2022 World Health Organization classification: a 23-year retrospective analysis

 

n = 80

Age (years, range)

64(30–81)

Sex

Male / Female

44 (55%) / 36 (45%)

Diagnostic opportunity

Medical check-up / Follow-up for another disease / Detected by resected specimens / Abdominal pain

55 (68%) / 20 (25%) / 3 (4%) / 2 (3%)

Tumor location

Head / Body / Tail

31 (39%) / 24 (30%) / 25 (31%)

Surgical procedures

Major resection

40 (50%)

DP / PD / TP

21 / 18 / 1

Limited resection

40 (50%)

SPDP / PP / EN / CP

20 / 15 / 3 / 2

Number of dissected lymph node

4 (0–27)

 Postoperative complications

≥ III

26 (33%)

Ki-67 index (%, range)

2 (1–10)

 WHO 2022 classification

NET G1 / NET G2

60 (75%) / 20 (25%)

Pathological tumor size (mm, range)

12 (2–80)

 Local invasion

T1 / T2 / T3

58 (73%) / 13 (16%) / 9 (11%)

 Synchronous lymph node metastasis

With

4 (5%)

 Lymphatic invasion

With

14 (18%)

 Microvascular invasion

With

20 (25%)

 Perineural invasion

With

11 (14%)

 Recurrence

With (duplication)

6 (9%)

Liver / Paraaortic lymph node

6 / 1

Recurrent period after surgery (years, range)

2.0 (0.6–11.3)

Dead form NF-PanNEN

2 (3%)

Dead from another disease

9 (11%)

Postoperative observation period (years, range)

6.8 (0.3–23.3)

  1. Abbreviations: DP Distal pancreatectomy, PD Pancreaticoduodenectomy, TP Total pancreatectomy, SPDP Splenic preserving distal pancreatectomy, PP Partial pancreatectomy, EN Enucleation, CP Central pancreatectomy, WHO World Health Organization, NET Neuroendocrine tumor, NF-PanNEN Non-functioning pancreatic neuroendocrine neoplasm