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Table 1 Demographic and clinical characteristics between PG group and PJ group

From: Safety and efficacy of pancreaticogastrostomy for hepatopancreatoduodenectomy compared to pancreaticojejunostomy for perihilar cholangiocarcinoma

 

Total (N=50)

PG group (N=15)

PJ group (N=35)

P value

Patient backgrounds

    

 Age (years)

74 (50–82)

75 (51-82)

73 (50-82)

0.106

 Sex (female), n (%)

13 (26.0)

2 (13.3)

11 (31.4)

0.163

 Body mass index (kg/m2/)

20.9 (15.6-28.6)

21.5 (16.9-26.2)

20.4 (15.6-28.6)

0.227

Comorbidities

    

 Hypertension, n (%)

22 (44.0)

5 (33.3)

17 (48.6)

0.116

 Diabetes mellitus, n (%)

14 (28.0)

6 (40.0)

8 (22.9)

0.308

 Vascular disease*, n (%)

11 (22.0)

4 (26.7)

7 (20.0)

0.560

 Charlson Risk Index

4 (1-7)

4 (2-7)

4 (1-7)

0.171

 Serum albumin, (g/dL)

3.5 (2.4–4.3)

3.8 (3.1-4.3)

3.5 (2.4-4.3)

0.180

 Serum CEA (ng/mL)

2.4 (0.6–5.6)

3.0 (0.6-4.7)

2.3 (0.6-5.6)

0.847

 Serum CA19-9 (U/mL)

45 (2–3716)

42 (10-1386)

53 (2-3716)

0.761

Type of cancer, n (%)

   

0.173

 Bile duct cancer

44 (88.0)

15 (100.0)

29 (82.9)

 

 Gallbladder cancer

4 (8.0)

0

4 (11.4)

 

 Intrahepatic cholangiocarcinoma

2 (4.0)

0

2 (5.7)

 

NAC or NACRT, n (%)

13 (26.0)

3 (20.0)

10 (28.5)

0.398

Preoperative biliary drainage, n (%)

44 (88.0)

15 (100)

29 (82.9)

0.306

ICG-15R (%)

9.6 (2.0–22.4)

12.0 (6.5-18.2)

8.1 (2-22.4)

0.118

PTPE, n (%)

41 (82.0)

11 (73.3)

30 (85.7)

0.254

Future remnant liver volume (%)

52.1 (33.7–82.0)

46.9 (37.3-69.0)

52.2 (34.4-82.0)

0.403

Remnant ICG-K

0.075 (0.040-0.157)

0.069 (0.049-0.108)

0.080 (0.040-0.157)

0.126

Distance between HJ and PG/PJ (mm)

52.7 (16.3-121.8)

100.2 (78.6-121.8)

42.0 (18.3-87.3)

<0.001

Distance between the dissected artery and PG/PJ (mm)**

24.3 (5.1-72.1)

51.0 (27.3-72.1)

19.4 (5.1-56.5)

<0.001

Operative data

    

Type of hepatectomy, L3/C2/L2/R2/R3

1/5/16/27/1

0/3/4/8/0

1/2/12/19/1

0.526

 Combined vascular resection, PV/HA/PV+HA

14/2/8

4/1/1

10/1/7

0.581

 Operation time (min)

806 (323-1375)

911 (417-1150)

720 (323-1375)

0.097

 Blood loss (ml)

625 (195-2368)

520 (240-1905)

740 (195-2368)

0.384

 Intraoperative RBC transfusion, n (%)

25 (50.0)

7 (46.7)

18 (51.4)

0.462

 Postoperative short-term outcomes

    

Major morbidity (CDIIIa), n (%)

38 (76.0)

9 (60.0)

29 (82.9)

0.087

 postoperative massive ascites (ml)

1076 (160-3971)

830 (168-3280)

1220 (160-3971)

0.147

 postoperative massive ascites (1,500 ml/day)***

18 (36.0)

2 (13.3)

16 (45.7)

0.028

 Postoperative bile leakage, n (%)

6 (12.0)

2 (13.3)

4 (11.4)

0.591

 Post hepatectomy liver failure, n (%)

11 (22.0)

1 (6.7)

10 (28.6)

0.085

 Postoperative pancreatic fistula, n (%)

19 (38.0)

0 (0)

19 (54.3)

<0.001

 Postoperative artery bleeding, n (%)

8 (16.0)

1 (6.7)

7 (20.0)

0.232

 Hospital stays (days)

42 (23-168)

39 (31-94)

54 (23-168)

0.415

 Postoperative 90-day mortality, n (%)

1 (2.0)

0 (0)

1 (2.9)

0.700

 In-hospital death, n (%)

3 (6.0)

0 (0)

3 (8.6)

0.415

Postoperative pathological data

    

 Lymph node metastasis, n (%)

33 (66.0%)

12 (80.0)

21 (60.0)

0.434

 Resection margin, 0/1/2

35/16/1

9/6/0

24/10/1

0.737

  1. Data was presented as median values (minimum-maximum values)
  2. Abbreviations; CD, Clavien-Dindo. CHA, common hepatic artery. C2, central bisectionectomy. HA, hepatic artery. HJ, hepaticojejunostomy. L2, left hepatectomy. L3, left trisectionectomy. NAC, Neoadjuvant chemotherapy. NACRT, neoadjuvant chemoradiotherapy. PG, pancreaticogastrostomy. PJ, pancreaticojesunostomy. PTPE, percutaneous transhepatic portal vein embolization. PV, portal vein. RBC, red blood cell. R2, right hepatectomy. R3, right trisectionectomy
  3. *Cardiovascular disease, cerebral vascular disease, etc
  4. **The distance between the PG/PJ anastomosis and the dissected artery closest to the PG/PJ anastomosis (e.g., common hepatic artery, gastroduodenal artery, proper hepatic artery, and left/right hepatic artery)
  5. ***Intraabdominal drain discharge more than 1,500mL/day during post operative 7 days