Table 1 Demographic and clinicopathologic characteristics of 519 Chinese patients with CRLM undergoing liver resection
characteristics | Â | value |
|---|---|---|
Age, median (IQR) |  | 58 (52–64) |
Sex, male: female | Â | 358:161 |
Primary tumor site | Right colon | 99 (19.1%) |
| Â | Left colon or rectum | 420 (80.9%) |
T stage | T1-T2 | 42 (8.4%) |
| Â | T3-T4 | 460 (91.6%) |
| Â | NA | 17 |
Lymph node metastases of primary tumor | negative | 162 (32.1%) |
| Â | positive | 343 (67.9%) |
| Â | NA | 14 |
Disease-free interval (months) | < 12 | 390 (75.1%) |
|  | ≥ 12 | 129 (24.9%) |
Therapy before surgery | No treatment | 94 (18.1%) |
| Â | Chemotherapy | 268 (51.6%) |
| Â | Chemotherapy with anti-VEGF agents | 158 (30.4%) |
| Â | Chemotherapy with anti-EGFR agents | 149 (28.7%) |
Cycles of treatments before surgery | > 6 | 104 (20.0%) |
|  | ≤ 6 | 321 (61.8%) |
Response to preoperative chemotherapy n (% in patients receiving chemotherapy) | PR | 199 (47.5%) |
| Â | SD | 200 (47.7%) |
| Â | PD | 20 (4.8%) |
| Â | NA | 6 |
Preoperative CEA (ng/ml), median (IQR) |  | 7.14 (3.32–20.5) |
Number of liver metastases | > 1 | 361 (69.6%) |
| Â | 1 | 158 (30.4%) |
Diameter of the largest CRLM (cm), median (IQR) |  | 2.5 (1.70–3.75) |
Major hepatectomy | Â | 127 (24.5%) |
Resection margin | R0 | 431 (83.0%) |
| Â | R1 | 88 (17.0%) |