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Table 3 Diagnostic value of C125, CA199, CEA and AFP in GC

From: The combination of CA125, CA199, CEA, and AFP is an effective diagnostic biomarker for gastric cancer in elderly individuals

Tumour marker

Cut-off value

Sensitivity (%)

Specificity (%)

Positive predictive value(%)

Negative predictive value(%)

CA199

37.00IU/mL

29.21

100

100

42.73

5.305 IU/mL

91.01

87.23

93.1

83.67

CEA

5.09 ng/mL

31.46

97.98

96.55

42.99

3.07 ng/mL

53.93

82.98

85.71

48.75

CA125

35.00 IU/mL

44.94

100

100

48.96

AFP

7.00 IU/mL

24.72

97.87

95.65

40.71

7.20 IU/mL

24.72

100

100

41.23

Combination

Ā 

65.17

95.74

96.67

59.21

0.741

98.85

85.11

92.63

85.56