Fig. 6

Prognostic model evaluation and immune infiltration analysis in pancreatic cancer. A Venn diagram depicting the overlap between significant genes identified by one-way Cox regression and trajectory genes with significant changes identified by Monocle. B Kaplan–Meier (K-M) survival curves for the 5-gene prognostic model in the training set. C Kaplan–Meier survival curves for the 5-gene prognostic model in the validation set. D Kaplan–Meier survival curves for the 5-gene prognostic model across the entire dataset. E, F ROC curves assessing model performance with AUCs at 1, 5, 7, and 10 years for both the training set and the entire dataset. G Immunological infiltration in high- and low-risk groups, as determined by the model, assessed using the CIBERSORT approach. H Violin plots revealing immune cell infiltration across different categories. I Correlation analysis between KLF6 expression and immune infiltration levels of M2 macrophages, neutrophils, and Tregs