Fig. 1

Identification and characterization of E2F-based subtypes in TCGA-HNSC. (A) Two subtypes were identified. (B) Overall survival differed significantly between the two subtypes (p < 0.05). (C) E2F expression was significantly lower in Cluster 1 compared to Cluster 2. TCGA, The Cancer Genome Atlas; HNSC, head and neck squamous cell carcinoma