Missing | In analysis, | Univariate analysis | p-value | Multivariate analysis | p-value | |
---|---|---|---|---|---|---|
data, n | n | HR (95% CI) | HR (95% CI) | |||
Age: | 43 | |||||
< 65 years | 299 | ref. | ||||
≥ 65 years | 242 | 1.037 (0.773–1.391) | 0.809 | |||
Sex: | 42 | |||||
Male | 249 | 1.043 (0.777–1.399) | 0.78 | |||
Female | 293 | ref. | ||||
Neoadjuvant chemo: | 164 | |||||
Yes | 127 | 1.376 (0.978–1.934) | 0.067 | 1.815 (1.059–3.110) | 0.03 | |
No | 293 | ref. | ||||
Any complication : | 48 | |||||
Yes | 311 | 1.663 (1.205–2.295) | 0,002 | |||
No | 225 | ref. | ||||
Severe complication : | 33 | |||||
Yes | 72 | 2.112 (1.373–3.249) | < 0.001 | 2.390 (1.385–4.127) | 0.002 | |
No | 225 | ref. | ||||
Not in analysis (CD 1-3a) | 254 | |||||
Duration of surgery: | 60 | |||||
< 480 min | 267 | ref. | ||||
≥ 480 min | 257 | 1.313 (0.975–1.769) | 0.073 | 0.652 (0.382–1.113) | 0.117 | |
Postop leukopenia: | 40 | |||||
Yes | 47 | 0.877 (0.508–1.514) | 0.638 | |||
No | 497 | ref. | ||||
Severe leukopenia: | 38 | |||||
Yes | 27 | 1.678 (0.934–3.015) | 0.083 | 1.357 (0.448–4.111) | 0.589 | |
No | 497 | ref. | ||||
Not in analysis (mild leukopenia) | 22 | |||||
PCI-score: | 45 | |||||
0–8 | 265 | ref. | ref. | |||
9–15 | 159 | 2.084 (1.464–2.965) | < 0.001 | 2.318 (1.239–4.335) | 0.009 | |
> 15 | 115 | 2.632 (1.822–3.801) | < 0.001 | 2.598 (1.313–5.141) | 0.006 | |
pN-stage: | 66 | |||||
N0 | 107 | ref. | ref. | |||
N1 | 181 | 1.902 (1.118–3.234) | 0.018 | 0.915 (0.392–2.138) | 0.837 | |
N2 | 227 | 2.991 (1.809–4.944) | < 0.001 | 1.844 (0.866–3.927) | 0.113 | |
Nx | 3 | |||||
Period of surgery: | 40 | |||||
2019–2021 | 201 | ref. | ref. | |||
2016–2018 | 213 | 1.546 (1.070–2.234) | 0.02 | 1.487 (0.748–2.954) | 0.257 | |
2013–2015 | 109 | 1.541 (1.008–2.355) | 0.046 | 1.019 (0.467–2.226) | 0.962 | |
≤ 2012 | 21 | 1.425 (0.669–3.034) | 0.358 | 0.842 (0.210–3.368) | 0.808 |