Mediator | Total effect β (95%CI) | Direct effect a β(95%CI) | Direct effect b β(95%CI) | Mediation effect β (95%CI) | Mediated Proportion (%) |
|---|
CCL4 | 1.266(0.165 to | 0.111(0.001 to | 0.582(0.263 to | 0.065(0.001 to | 5.134 |
| Â | -2.367) | 0.221) | 0.902) | 0.151) | Â |
- ‘Total effect’ indicates the effect of genus Ruminococcaceae UCG005 on mesothelioma, ‘direct effect a’ indicates the effect of genus Ruminococcaceae UCG005 on CCL4, ‘direct effect b’ indicates the effect of CCL4 on mesothelioma and ‘mediation effect’ indicates the effect of genus Ruminococcaceae UCG005 on mesothelioma through CCL4. Total effect, direct effect a and b were analyzed by IVW; mediation effect was analyzed by delta method
