Fig. 1
From: SDC1 is a critical transmembrane proteoglycan in breast cancer
The cellular activities of SDC1 in breast cancer. Proliferation and migration:SDC1: Syndecan1; RTK: Receptor Tyrosine Kinase; FAK: Focal adhesion kinase; SRC: Sarcoma. Cell apoptosis: Caspase 3/Caspase 9 signal pathway; MEK/ERK signal pathway; JunB/Flip signal pathway; PDK1/AKT/BAD signal pathway. Cell cycle:G1: First Gap; S: Synthesis; M: Metaphase; G2: Second Gap. BCSC phenotype:IL-6: Interleukin-6; EGF (R): Epidermal Growth Factor (Receptor); STAT3: Signal Transducer and Activator of Transcription 3; Notch signal pathway; NF-KB: Nuclear Factor Kappa-B