From: Prognostic significance of T cells and NK cells in osteosarcoma: a dual-center retrospective study
Variable | HR (95%) | P-value |
---|---|---|
Gender (Female vs. Male) | 0.893(0.522–1.528) | 0.680 |
Age (years) | 1.026(1.010–1.043) | 0.002 |
BMI (kg/m2) | 1.081(1.002–1.166) | 0.045 |
WBC (109/L) | 1.033(0.996–1.071) | 0.081 |
CRP (mg/L) | 1.007(1.000-1.013) | 0.040 |
Tumor size (≥ 355.96 cm3 vs. <355.96 cm3) | 2.058(1.212–3.494) | 0.008 |
Enneking stage |  | < 0.001 |
 I | 1 |  |
 II | 14.753(1.988-109.478) | 0.008 |
 III | 49.848(6.693-371.236) | < 0.001 |
Primary site | Â | 0.140 |
 Others | 1 |  |
 Upper limb | 0.288(0.077–1.077) | 0.064 |
 Lower limb | 0.579(0.282–1.188) | 0.136 |
Pathological type | Â | Â |
 (Conventional vs. Others) | 0.498(0.197–1.258) | 0.140 |
Surgical method |  | < 0.001 |
 No | 1 |  |
 Amputation | 0.536(0.278–1.033) | 0.062 |
 Resection | 0.270(0.145–0.502) | < 0.001 |
Chemotherapy | Â | 0.071 |
 Yes | 1 |  |
 No | 1.885(0.948–3.749) |  |
Radiotherapy | Â | 0.530 |
 Yes | 1 |  |
 No | 1.885(0.260-13.658) |  |
T-cell proportion (≥ 0.741 vs. <0.741) | 0.364(0.192–0.688) | 0.002 |
NK-cell proportion (≥ 0.099 vs. <0.099) | 0.366(0.208–0.644) | < 0.001 |
B -cell proportion (≥ 0.103 vs. <0.103) | 1.984(1.099–3.580) | 0.023 |