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  1. This study aims to compare and evaluate the clinical efficacy of laparoscopic capsule-preserving resection (LCPR) and laparoscopic partial nephrectomy (LPN) in the treatment of renal angiomyolipoma (RAML). Mul...

    Authors: Haipeng Zhang, Guangcan Yang, Changxiu Tian, Wei Song, Houliang Zhang, Jinliang Ni, Ziming Jiang, Keyi Wang and Bo Peng
    Citation: World Journal of Surgical Oncology 2025 23:151
  2. This study examines the cellular heterogeneity of epithelial cells within pancreatic ductal adenocarcinoma (PDAC) and their contributions to tumor progression, metastasis, and immunosuppressive interactions us...

    Authors: Jie Liu, Hui Li, Xiuyun Lin, Jiani Xiong, Guangfeng Wu, Lingyan Ding and Bin Lin
    Citation: World Journal of Surgical Oncology 2025 23:144
  3. In recent years, triple therapy (molecular targeted agent + PD-1 inhibitor + transarterial therapy) has emerged as a promising strategy for unresectable hepatocellular carcinoma (uHCC). However, the optimal mo...

    Authors: Yaohong Wen, Shuyi Zhou, Yuyan Xu, Cheng Zhang, Zhoubin Feng, Yinghui Song, Bai Ding, Chuang Peng, Hongkun Tan, Chunming Wang, Jianan Feng, Jingyuan Pei, Guolin He, Shunjun Fu, Lvhuan Wang, Lei Cai…
    Citation: World Journal of Surgical Oncology 2025 23:143
  4. Serum tumour markers (TMs) such as alpha-fetoprotein (AFP), carcinoembryonic antigen (CEA), carbohydrate antigen 199 (CA199) and CA125 have been established as prognostic indicators for gastric cancer (GC); ho...

    Authors: Xiao-wen Yuan, Jia-hao Feng, De bing Huang, Zhan-tao Lu, Hui-ling Ye, Ping Chen and Lv Deng
    Citation: World Journal of Surgical Oncology 2025 23:142
  5. Gastric cancer (GC) has a high global mortality and incidence rate. Lymph node (LN) invasion is crucial in TNM staging, and an accurate LN staging system is vital for treatment decisions. However, the appropri...

    Authors: Rui Li, Xu Sun, Zhiyuan Yu, Xiangchao Zhu, Xudong Zhao, Peiyu Li and Na Liu
    Citation: World Journal of Surgical Oncology 2025 23:141
  6. To develop and validate a predictive model for stent patency following a palliative self-expandable metallic stent (SEMS) for primary malignant colonic obstruction.

    Authors: Yuan Wan, Meng-sha Zou, Zhao-fei Zeng, Xiao-zheng Cao, Huan-hua Wu and Bo Zhang
    Citation: World Journal of Surgical Oncology 2025 23:140
  7. Perforated colorectal cancer exhibits a higher recurrence rate than non-perforated colorectal cancer; however, the reasons for this difference remain unclear. This study identifies factors affecting recurrence...

    Authors: Makoto Takagi, Seongcheol Kim, Masaomi Suzuki, Tetsuyoshi Takayama and Hiroshi Asano
    Citation: World Journal of Surgical Oncology 2025 23:139
  8. Repeat cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) (rCRS-HIPEC) has improved the long-term survival of select patients with acceptable perioperative morbidity and mortalit...

    Authors: Celine Garrett, Louise Sun, Raymond Hayler, Ruwanthi Wijayawardana, Nima Ahmadi, Mina Sarofim and David L. Morris
    Citation: World Journal of Surgical Oncology 2025 23:138
  9. This study aimed to assess the oncological safety of nipple- and areola-sparing mastectomy (NSM) compared to mastectomy without preservation of the nipple-areola complex (NAC) in patients with breast cancer pr...

    Authors: Hong Hou, Jing Xia, Lin Tan, Yue Yu and Xin Wang
    Citation: World Journal of Surgical Oncology 2025 23:137
  10. Thoracic epidural analgesia (TEA) is the gold standard for analgesia after thoracotomy, but it has limitations. There are few studies on the analgesic effect of ultrasound-guided paravertebral nerve block (PVB...

    Authors: Tingting Yang and Yuan He
    Citation: World Journal of Surgical Oncology 2025 23:136
  11. Deep learning(DL) models can improve significantly discrimination of lymph node metastasis(LNM) of pancreatic ductal adenocarcinoma(PDAC), but have not been systematically assessed.

    Authors: Xia Ding, Wei Xu, Yan Xu, Yongchuang Zhang, Huaxiao Xu, Lin Guo and Lei Li
    Citation: World Journal of Surgical Oncology 2025 23:135
  12. There is still controversy regarding the safety and efficacy of atezolizumab for the treatment of urothelial carcinoma (UC). This research aimed to extensively investigate the effectiveness and safety of atezo...

    Authors: Jun Xie, Qiu-yu Mao, Jun-hao Chen, Hong-jin Shi, Pei-qin Zhan and Hai-feng Wang
    Citation: World Journal of Surgical Oncology 2025 23:133
  13. Surgery-based multimodality therapies for treatment of malignant pleural mesothelioma have been clinically explored in the past decades. In this regard, hyperthermic intrathoracic or intrapleural chemotherapy ...

    Authors: Hany Hasan Elsayed, Mohamed Elanany Elsaid Elanany, Mohamed Tarek ElSayegh, Aly Sherif Hassaballa and Mohammed Abdel-gayed
    Citation: World Journal of Surgical Oncology 2025 23:132
  14. The tertiary lymphoid structures (TLSs) are positively correlated with the prognosis of many solid tumors, including colorectal cancer. However, their prognostic significance in patients with locally advanced ...

    Authors: Yingjian Jiang, Chuang Zhang, Yifei Hou, Bin Zhao and Binbin Cui
    Citation: World Journal of Surgical Oncology 2025 23:131
  15. There is no study on the relationship between peripheral blood different lymphocyte subtypes and the prognosis of osteosarcoma (OS). Therefore, this study aims to investigate the predictive value of T cells an...

    Authors: Kai Luo, Haijun Tang, Weijie Yan, Shanhang Li, Xiaoting Luo, Mingxiu Yang, Feicui Li, Jiming Liang, Shijie Liao, Yun Liu, Juliang He and Dehuai H. Liu
    Citation: World Journal of Surgical Oncology 2025 23:130
  16. Cutaneous squamous cell carcinoma (cSCC) is a type of skin tumor that develops in the epithelial cells. This disease has the second highest incidence of human skin cancers, with a high metastatic rate. While u...

    Authors: Zijian Zhang, Lili Liang, Xiaoke Jiang, Jixuan Shan, Siying Li, Jie Liu, Qinyi Dong, Xinman Wang and Han Zhang
    Citation: World Journal of Surgical Oncology 2025 23:129
  17. Robot-assisted Thoracic Surgery (RATS) is well-established for complex minimally invasive thoracic surgery. Despite the available literature, robotics for complex advanced NSCLC for re-do surgery remains under...

    Authors: Ghada Shahin, Rohit Kharbanda, Quirijn Tummers and Jerry Braun
    Citation: World Journal of Surgical Oncology 2025 23:128
  18. The debate over the optimal reconstruction technique following proximal gastrectomy continues. Transhiatal tunnel valvuloplasty (ThTV) is a novel esophagogastrostomy method. This study aimed to evaluate the fe...

    Authors: Chunguang Guo, Zefeng Li, Xin Guo, Yong Liu, Dong Qu, Zhaodong Xing, Hu Ren, Chongyuan Sun, He Fei, Xiaojie Zhang, Lei Ge, Yanwei Gao, Enjun Li, Chaodong Yin, Jing Zhang, Guiqi Wang…
    Citation: World Journal of Surgical Oncology 2025 23:127
  19. Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality worldwide, and advanced-stage disease presents significant therapeutic challenges. Combining transarterial chemoembolization (TACE)...

    Authors: Hengyu Tian and Chidan Wan
    Citation: World Journal of Surgical Oncology 2025 23:126
  20. Internationally, evidence supporting robotic liver resection (RLR) has gradually increased in recent years. However, a standardized protocol for RLR remains lacking. This study describes a surgical protocol an...

    Authors: Kosei Takagi, Tomokazu Fuji, Kazuya Yasui, Yuzo Umeda, Motohiko Yamada, Takeyoshi Nishiyama, Yasuo Nagai, Noriyuki Kanehira and Toshiyoshi Fujiwara
    Citation: World Journal of Surgical Oncology 2025 23:124
  21. The incidence of rectal cancer (RC) among obese patients is gradually increasing. Obesity can elevate the risk of RC surgery in numerous aspects. This paper aims to compare the perioperative results of robotic...

    Authors: Hang Li, Li Xu, Xiping Shen and Xiaosong Li
    Citation: World Journal of Surgical Oncology 2025 23:123
  22. Lung adenocarcinoma(LUAD) is the primary reason for cancer-related deaths globally. GINS1 has a significant regulatory function in DNA replication. It is overexpressed in various malignant tumors, but the spec...

    Authors: Luyuan Ma, Rongyang Li, Pengyong Li, Wenhao Yu, Zhanpeng Tang, Libo Si and Hui Tian
    Citation: World Journal of Surgical Oncology 2025 23:122
  23. Locally advanced gastric cancer (LAGC) is challenging to treat, with neoadjuvant chemotherapy (NCT) improving survival. Recent advances suggest that neoadjuvant immunochemotherapy (NICT) may enhance treatment ...

    Authors: Chaofeng Li, Yu Duan, Shengnan Zhou, Tao Tang, Yinmo Yang and Lei Zhou
    Citation: World Journal of Surgical Oncology 2025 23:121
  24. This study aimed to analyze the clinical efficacy of π-shaped esophagojejunostomy and the overlap method in treating upper gastric cancer with double-tract reconstruction in proximal gastrectomy under total la...

    Authors: He Han, Zhiyuan Li, Yunfan Li, Liwen Zhang, Jixiang Chen, Qinjin Li and Xin Fan
    Citation: World Journal of Surgical Oncology 2025 23:120
  25. Cytoreductive surgery serves as a cornerstone intervention for advanced epithelial ovarian cancer (EOC), yet some patients decline the procedure despite clinical recommendations. This study aimed to evaluate s...

    Authors: Lei Zhao, Gang Cheng, Xin Zhou, Congya Xu, Mengni Ge and Qin Zhou
    Citation: World Journal of Surgical Oncology 2025 23:119
  26. Studies have demonstrated an elevated risk of urological malignancies in individuals undergoing dialysis, which consequently leads to unfavorable prognoses and diminished quality of life for patients with end-...

    Authors: Junjiang Ye, Biao Ran, Yin Huang, Zeyu Chen, Ruicheng Wu, Dengxiong Li, Puze Wang, Bo Chen, Ping Han and Liangren Liu
    Citation: World Journal of Surgical Oncology 2025 23:118
  27. Periprosthetic infections pose a devastating complication in skeletally immature patients treated for an orthopaedic oncological condition. Reconstructive approaches to revision procedures are often limited, a...

    Authors: Jan Lesensky, Ana C. Belzarena and Michal Benes
    Citation: World Journal of Surgical Oncology 2025 23:116
  28. Osteosarcoma is a common bone tumor in adolescents and children, characterized by rapid progression, high malignancy, poor prognosis, and a tendency for pulmonary metastasis. Despite extensive research efforts...

    Authors: Jun He, Liyang Yin, Qiong Yuan, Xiaotao Su, Yingying Shen and Zhongliang Deng
    Citation: World Journal of Surgical Oncology 2025 23:115
  29. The prognostic significance of the C-reactive protein-albumin-lymphocyte (CALLY) index in digestive system neoplasms (DSNs) has been investigated in several studies, but inconsistencies remain between the resu...

    Authors: Dengzhuo Chen, Yongli Ma, Jinghui Li, Liang Wen, Linfeng Liu, Jiarui Su, Jiawei Wu, Ping Wang, Guosheng Zhang, Chengzhi Huang and Xueqing Yao
    Citation: World Journal of Surgical Oncology 2025 23:114
  30. Pancreatic atrophy can occur after gastric cancer surgery, but the influencing factors and effects of pancreatic atrophy have not been extensively studied. The aim of this study was to investigate the factors ...

    Authors: Zhaoping Li, Lianlian Cao, Hao Chen, Feng Wang, Liang Tao and Meng Wang
    Citation: World Journal of Surgical Oncology 2025 23:112
  31. In primary cutaneous melanoma (CM) with metastatic sentinel lymph node(s) (SLNB), treatment strategies may include completing a regional lymph node dissection (CLND). The prognostic benefit of this therapeutic...

    Authors: Alessandra Buja, Massimo Rugge, Chiara Trevisiol, Anna Zanovello, Marcodomenico Mazza, Luigi Dall’Olmo, Manuel Zorzi, Antonella Vecchiato, Paolo Del Fiore, Carlo Riccardo Rossi and Simone Mocellin
    Citation: World Journal of Surgical Oncology 2025 23:111
  32. Various anti-reflux procedures are currently utilized for digestive tract reconstruction following proximal gastrectomy (PG), but the optimal reconstruction method remains debated. This study aims to compare a...

    Authors: Zhu Jingtao, Chen Shaoqin, Zhang Tao, Yang Li, You Sheng, Hong Qingqi, Lin Hexin, Chen Yinan, Yu Huangdao, Chen Yifu, Yu Xuejun and You Jun
    Citation: World Journal of Surgical Oncology 2025 23:110
  33. Breast cancer (BCa) is the leading cause of cancer-related death among women worldwide. MicroRNAs (miRNAs) are promising tools for diagnosis and prognosis. This study investigated the role of serum miRNAs and ...

    Authors: Xiaohui Li, Feng Wang, Faquan Lin, Binbin Xie, Yi Liu, Yi Xiao, Kai Qin, Weicheng Li and Qiyan Zeng
    Citation: World Journal of Surgical Oncology 2025 23:109
  34. Adipocyte enhancer-binding protein 1 (AEBP1) regulates collagen fibrosis, extracellular matrix, and important oncogene pathways, but its regulation on hepatocellular carcinoma (HCC) is not known. This study ai...

    Authors: Liyou Liu, Qingshan Cai, Dongyang Wu, Shudong Li, Dong Liu and Jianxing Zheng
    Citation: World Journal of Surgical Oncology 2025 23:108
  35. Neuropilin and tolloid-like 2 (NETO2) facilitates the progression of various cancers, but its role in hepatocellular carcinoma (HCC) is not known. This study aimed to assess the potential of targeting NETO2 in...

    Authors: Na Shun Meng He, Xinghua Wu, Shu Chen, Xinyi Yun, Shun Yao and Hai Yu
    Citation: World Journal of Surgical Oncology 2025 23:107
  36. The present case of a colorectal adenocarcinoma at the anastomotic site of a colorectal anastomosis after childhood surgery for Hirschsprung disease is a rare report of such pathology. Possibly, the altered an...

    Authors: Matthias Mehdorn, Philipp Rhode, Jan-Hendrik Gosemann, Katja Grunwald, Hans-Jonas Meyer, Martin Lacher and Sigmar Stelzner
    Citation: World Journal of Surgical Oncology 2025 23:105
  37. This study aimed to develop predictive models for postoperative recurrence and overall survival in patients with brain glioma (BG) by integrating preoperative contrast-enhanced MRI-derived delta habitat radiom...

    Authors: Xiumei Li, Lina Song, Haidong Zhang, Xianqun Ji, Ping Song, Junjie Liu and Peng An
    Citation: World Journal of Surgical Oncology 2025 23:104
  38. The immediate perioperative period (IPP) usually is highly stressful and has significant effects on the postoperative recurrence/metastasis of tumors. Effective methods for limiting the impact of the IPP on po...

    Authors: Shanqing Xu, Yongzhong Tang and Jianbin Tong
    Citation: World Journal of Surgical Oncology 2025 23:103
  39. Accurate preoperative evaluation for metastatic lesions is significant for PTC patients. However, the stratification systems revealed inconsistencies in the ultrasound (US) features of cervical metastatic lymp...

    Authors: Hai-Long Tan, Sai-Li Duan, Qiao He, Zhe-Jia Zhang, Peng Huang and Shi Chang
    Citation: World Journal of Surgical Oncology 2025 23:102
  40. Ductal carcinoma in situ (DCIS) is considered a precursor to invasive ductal carcinoma (IDC), and the coexistence of DCIS with IDC is often observed during the diagnosis of breast cancer. The aim of study is t...

    Authors: Sicheng Zhou, Li Liang, Zehao Huang, Yue Teng and Wei Xing
    Citation: World Journal of Surgical Oncology 2025 23:101
  41. In patients with early gastric cancer (EGC) who undergo endoscopic submucosal dissection (ESD) with endoscopic curability (eCura) C-2, the risk of non-gastric cancer mortality should be evaluated before receiv...

    Authors: Xiao Shi, Xiaoyi Shi, Yuxing Yan and Aixia Gong
    Citation: World Journal of Surgical Oncology 2025 23:100
  42. Prostate cancer (PCa) is the second most common cancer among men worldwide. This study uses data from the 2021 Global Burden of Disease (GBD) study to estimate the global burden of prostate cancer from 1990 to...

    Authors: Feifan Chu, Lumin Chen, Qing Guan, Zujie Chen, Qiwei Ji, Yuning Ma, Jinzhong Ji, Mingxin Sun, Tingyang Huang, Haihan Song, Hao Zhou, Xiuquan Lin and Yichun Zheng
    Citation: World Journal of Surgical Oncology 2025 23:98
  43. Hepatopancreatoduodenectomy (HPD) is one of the most challenging surgeries for perihilar cholangiocarcinoma. Postoperative pancreatic fistula (POPF) is a critical and fatal complication. The safety and efficac...

    Authors: Yutaka Nakano, Yuta Abe, Daisuke Udagawa, Minoru Kitago, Yasushi Hasegawa, Shutaro Hori, Masayuki Tanaka, Sho Uemura, Masanori Odaira, Kisyo Mihara, Ryo Nishiyama, Naokazu Chiba, Shigeo Hayatsu, Shigeyuki Kawachi and Yuko Kitagawa
    Citation: World Journal of Surgical Oncology 2025 23:97

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